burn wound The skin contains epithelium, which is made up of cells that act as barriers between the internal body contents and the external environment. Being the largest body organ, the skin plays an important role in protecting other internal organs. The various three layers, epidermis dermis and hypodermis, are important in achieving the protective function. When tissue burns occur, they involve coagulation and microvascular reactions. Severe burns lead to the loss of skin barrier, increasing vasoactive mediators’ production from the injured areas. Pathophysiology It is important to understand the pathophysiology of a burn wound for better management. There are different injury patterns caused by different causes. When the body temperatures rise above the optimal value, there is a risk
