MANIFESTATION AND TRANSMISSION OF COVID-19 IN ASYMPTOMATIC CARRIERS.
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Introduction
The ongoing Covid-19 outbreak first occurred in Wuhan, China. Officially, the world health organization named the virus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)[1]. Numerous studies cover the nature, symptoms, and prevention of Covid-19. However, very few have focused on the asymptomatic carriers of the virus. A study on the manifestation and transmission of covid-19 in asymptomatic carriers would need to investigate several questions. How can the virus be identified in asymptomatic carriers? What is the dormant nature of the virus? What are the transmission rate and patterns of transmission?
Literature Review
Several aspects of covid-19 are essential for a study of the asymptomatic factor of covid-19 is to be effectively carried out. The origin and etiology of the virus, covered in ‘Interspecies transmission and emergence of novel viruses: lessons from bats and birds’[2]. The transmission and control of the virus is another important factor. ‘Early dynamics of transmission and control of covid-19: mathematical modelling study’[3] gives a unique yet comprehensive coverage of the spread-pattern of the virus.
Currently, some studies cover the transmission of covid-19 through asymptomatic carriers. ‘Presumed asymptomatic carrier transmission of covid-19′[4] Moreover, ‘Clinical characteristics of 24 asymptomatic infections with covid-19 screened among close contacts in Nanjing, china’[5] are examples of such studies. In both pieces of research, the focus was on the physical manifestation of the virus in asymptomatic carriers.
Methodology.
Comparing the results of the medical examination of a healthy control group, asymptomatic carriers, and symptomatic carriers are the best ways to determine the virus’s manifestation. The three groups undergo real-time reverse transcription-polymerase chain reaction tests and CT imaging. Furthermore, observing and comparing the transmission pattern around each participant would help identify asymptomatic transmission patterns.
Relevance.
The study of asymptomatic carriers of covid-19 is crucial for several reasons. First, identifying the dormant nature of the virus helps scientists understand the virus and may apply to other types of research. Identifying the transmission pattern and manifestation of the virus will help to reduce human to human infections from asymptomatic carriers. Countries will also be able to create policies that prevent the travel and interaction of asymptomatic carriers with the general public.
Bibliography
Bai, Yan, Lingsheng Yao, Tao Wei, Fei Tian, Dong-Yan Jin, Lijuan Chen, and Meiyun Wang. “Presumed asymptomatic carrier transmission of COVID-19.” Jama 323, no. 14 (2020): 1406-1407.
Chan, Jasper Fuk-Woo, Kelvin Kai-Wang To, Herman Tse, Dong-Yan Jin, and Kwok-Yung Yuen. “Interspecies transmission and emergence of novel viruses: lessons from bats and birds.” Trends in microbiology 21, no. 10 (2013): 544-555.
Hu, Zhiliang, Ci Song, Chuanjun Xu, Guangfu Jin, Yaling Chen, Xin Xu, Hongxia Ma et al. “Clinical characteristics of 24 asymptomatic infections with COVID-19 screened among close contacts in Nanjing, China.” Science China Life Sciences (2020): 1-6.
Kucharski, Adam J., Timothy W. Russell, Charlie Diamond, Yang Liu, John Edmunds, Sebastian Funk, Rosalind M. Eggo et al. “Early dynamics of transmission and control of COVID-19: a mathematical modelling study.” The lancet infectious diseases (2020).
World Health Organization. “Coronavirus disease 2019 (COVID-19): situation report, 72.” (2020).
Zheng, Ying-Ying, Yi-Tong Ma, Jin-Ying Zhang, and Xiang Xie. “COVID-19 and the cardiovascular system.” Nature Reviews Cardiology 17, no. 5 (2020): 259-260.
[1] Zheng, Ying-Ying, Yi-Tong Ma, Jin-Ying Zhang, and Xiang Xie. “COVID-19 and the cardiovascular system.” Nature Reviews Cardiology 17, no. 5 (2020): 259-260.
[2] “Interspecies transmission and emergence of novel viruses: lessons from bats and birds.” Trends in Microbiology 21, no. 10 (2013): 544-555.
[3] Kucharski, Adam J., Timothy W. Russell, Charlie Diamond, Yang Liu, John Edmunds, Sebastian Funk, Rosalind M. Eggo et al. “Early dynamics of transmission and control of COVID-19: a mathematical modelling study.” The lancet infectious diseases (2020).
[4] Bai, Yan, Lingsheng Yao, Tao Wei, Fei Tian, Dong-Yan Jin, Lijuan Chen, and Meiyun Wang. “Presumed asymptomatic carrier transmission of COVID-19.” Jama 323, no. 14 (2020): 1406-1407.
[5] Hu, Zhiliang, Ci Song, Chuanjun Xu, Guangfu Jin, Yaling Chen, Xin Xu, Hongxia Ma, et al. “Clinical characteristics of 24 asymptomatic infections with COVID-19 screened among close contacts in Nanjing, China.” Science China Life Sciences (2020): 1-6.