Streptococcus Pyogenes
Streptococcus pyogenes just like the wall structure of the Gram-Positive bacteria have thick peptidoglycan that is not only intercalated but also covered with protein as well as lipoteichoic and teichoic acid. In other words, they have gram-positive cocci, nonsporulating, and are nonmotile (Efstratiou, Androulla, and Theresa Lamagni, 86). Therefore, its gram stain reaction takes the form of scarlet fever, pharyngitis, and impetigo cellulitis. And, in clinics, they are identified through the process of screening blood agar plates for β-hemolytic colonies. Also, streptococcus pyogenes cell wall composition makes it more susceptible to antibiotics because some contain antigens which are similar to those of heart valve fibroblasts, skeletal, smooth muscle, human cardiac, neuronal tissues and smooth muscle (Ferretti, Stevens, and Fischetti, 66). In the long run, an antibiotic remains active in fighting against streptococcus pyogenes. Some of the antibiotic used includes amoxicillin, cephalosporin, and penicillin.
As discussed in Nadia, a 12-year-old female case study, I think that the introduction of antibiotic resistance and the misuse of antibiotics as pertaining to the symptoms presented was a good process. Streptococcus pyogenes tend to attack the body as the study indicated. Take for instance the various roles pyogenes play in streptococcal infection. That includes microcolony formation, epidermal keratinocytes adherence, and epithelial cells invasion; some of the many reasons explaining why the antibiotics were to be administered (Rohde, Manfred, and Patrick Cleary, 94). However; the pediatrician would have waited for the result before prescribing the antibiotics. One of the reasons behind the statement above is that there are many diseases associated with signs and symptoms like streptococcus pyogenes and its hard to confirm whether is strep throat or no. Instead, the pediatrician would have gathered the most appropriate result before administering the antibiotics. Because Nadia would be suffering from other conditions as well which could only be determined by the result gathered.
Works Cited
Efstratiou, Androulla, and Theresa Lamagni. “Epidemiology of Streptococcus pyogenes.” Streptococcus pyogenes: basic biology to clinical manifestations [Internet]. University of Oklahoma Health Sciences Center, (2017): 34-89.
Ferretti, J. J., D. L. Stevens, and V. A. Fischetti. “Molecular Basis of Serotyping and the Underlying Genetic Organization of Streptococcus pyogenes–Streptococcus pyogenes: Basic Biology to Clinical Manifestations.” (2016): 56-70.
Rohde, Manfred, and P. Patrick Cleary. “Adhesion and invasion of Streptococcus pyogenes into host cells and clinical relevance of intracellular streptococci.” Streptococcus pyogenes: Basic Biology to Clinical Manifestations [Internet]. University of Oklahoma Health Sciences Center, (2016): 23-97.