Memory loss is among the primary symptoms by patients who have Dementia and Alzheimer’s diseases
Memory loss is among the primary symptoms reported by caretakers and patients who have Dementia and Alzheimer’s diseases. Typically, the long-term declarative and the working memory the first parts to be affected in the earliest course of the two conditions. The impaired memory pattern and functions of an individual correlate with functional and structural parameters of the brain integrity. The pathology of the two disease conditions interferes with memories formation from both the neural network and the molecular level networks. The article elucidates more on the effects of Alzheimer’s And Dementia on memory defining each disease, timeline, progress, treatments in the prevention, and the researched cures for the disease.
Physicians would choose Alzheimer’s disease as one of the body condition that affects human memory. Alzheimer’s disease (AD) is the most and the common cause of Dementia. According to the current statistics, more than 30 million of the world’s population has Alzheimer’s Dementia. The world health organization has projected that the number of infections could triple for the next two decades. Alzheimer’s dementia incidences have increased from around 6% to 51%, making the condition common to the aging population. Alzheimer’s Dementia is a neurodegenerative and polygenetic disorder of the brain that shows the loss of neurons and synapses. Most of the patients develop the diseases at around 40 years, affecting the entire families due to variations and the encoding of the genes in presenilin-1 and presenilin-2 and the amyloid precursor proteins causing the Alzheimer’s disease. On the other hand, Dementia comprises social and thinking symptoms that interfere with an individual’s daily functioning. Both Dementia and Alzheimer’s disease are caused by stroke, head injuries, or b brain tumor. Dementia refers to a group of symptoms that impacts patients’ memories during AD
is the brain’s progressive disease that causes cognitive function and memory impairment.Both conditions are treatable, requiring lab tests and other medical diagnoses.
The Alzheimer’s disease(AD) clinically starts with memory complains affecting speech production, episodic memory, visual orientation, semantic and naming problems. Memory refers to the
process of storing, encoding, and retrieving information regarding inner and the outer stimuli or information presented to an organism nervous system used in positioning and reacting an organism toward stimuli. Different memories have different neurophysiological and neuroanatomical effects, correlating long-term vs. short-term memory and the declarative versus implicit memory. For example, short-term memory depends on the changes and synthesis of the de novo protein in the neuronal networks molecular components individually in the cortical areas attributed to various memory types. The independent context information is is typically stored in the declarative and the semantic memory storing information that is specific to a specific context for example, place and time. The information consolidation of hippocampus is essential in the long-term and the short term memory whose destruction could make the new memory storage impossible. In clinics, the neuropsychological test batteries, for example, CERAD examination, test scales and constructs, for example, the dementia rating scale investigates
the memory aspects over various ranges of cognitive domains
The patients are profiled about the test abnormalities and the health reference group
adjusted for education and age. The AD patients particularly display a cognitive profile consisting of impairments in various cognitive domains. The pattern could develop overtime, where the patients typically start displaying a progressive decay of memory. In most cases, the patients show increased sensitivity to the working memory measured for example, in digit span. Interestingly, the currently used medications in the AD treatment like memantine and acetylcholinesterase inhibitors partly work by maximizing the concentration and attention, particularly in the mild to moderate Alzheimer’s disease. When the brain problem or the atrophy progresses the neurological and psychiatric symptoms arises where the infected
patients developing challenges while swallowing thereby losing weight. The health problem results in subsequent pneumonia or aspiration leading to the death of the demented patients.
The exact cause and cure of Alzheimer’s and Dementia conditions are unknown although the recent National Institute on Aging and the Alzheimer’s Association have provided the new guidelines and criteria for the diagnosis of the diseases. It, therefore, marks a complete overhaul attempting to implement people’s understanding and advancement about the conditions in the disease diagnosis. The use of hippocampal atrophy, biomarkers, and the formalization of the earlier stages of the diseases, such as cognitive impairment have been purely intended for research and for diagnosing the conditions earlier. It is could e interesting to know why few people do not develop develop AD
given the increased prevalence of the disease, especially in the aging population. The physicians should provide subjective concerns on the cognitive decline to develop the cognive imparement with the neuropsychological and
pathological results and tests into Dementia. Also there are various pradigmata that have developed by researchers for testing the memory functions regarding animal modes although the procedure does not display the validated data that could be aligned with specific test significant in conducting human tests.